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Cytosolic access of Mycobacterium tuberculosis: critical impact of phagosomal acidification control and demonstration of occurrence in vivo.

Mycobacterium tuberculosis (Mtb) uses efficient strategies to evade the eradication by professional phagocytes, involving--as recently confirmed--escape from phagosomal confinement. While Mtb determinants, such as the ESX-1 type VII secretion system, that contribute to this phenomenon are known, the...

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主要な著者: Roxane Simeone, Fadel Sayes, Okryul Song, Matthias I Gröschel, Priscille Brodin, Roland Brosch, Laleh Majlessi
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2015-02-01
シリーズ:PLoS Pathogens
オンライン・アクセス:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004650&type=printable
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