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Global histone protein surface accessibility in yeast indicates a uniformly loosely packed genome with canonical nucleosomes

Abstract Background The vast majority of methods available to characterize genome-wide chromatin structure exploit differences in DNA accessibility to nucleases or chemical crosslinking. We developed a novel method to gauge genome-wide accessibility of histone protein surfaces within nucleosomes by...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Luke T. Marr, Josefina Ocampo, David J. Clark, Jeffrey J. Hayes
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2021-01-01
Rangatū:Epigenetics & Chromatin
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s13072-020-00381-5
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