Utility of optimal proportion of tumor-infiltrating lymphocytes as a prognostic prediction of clinical outcome in intrahepatic cholangiocarcinoma: a single institution retrospective analysis

Abstract Background Intrahepatic cholangiocarcinoma (iCCA), prevalent in Northeastern Thailand, presents challenges due to late diagnosis and metastasis. Prognostic factors are crucial. Tumor-infiltrating lymphocytes (TILs) hold promise as prognostic indicators and for immunotherapy, but their optim...

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Detalhes bibliográficos

Principais autores:	Waritta Kunprom, Nattaporn Poonsiri, Piyapharom Intarawichian, Prakasit Sa-Ngiamwibool, Sakkarn Sangkhamanon, Malinee Thanee, Watcharin Loilome, Attapol Titapun, Apiwat Jareanrat, Vasin Thanasukarn, Tharatip Srisuk, Vor Luvira, Kulyada Eurboonyanun, Julaluck Promsorn, Supinda Koonmee, Piya Prajumwongs, Chaiwat Aphivatanasiri
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-11-01
coleção:	Diagnostic Pathology
Assuntos:	Tumor-infiltrating lymphocytes Intrahepatic cholangiocarcinoma Early stage Prognosis Predicting outcome
Acesso em linha:	https://doi.org/10.1186/s13000-025-01733-z
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