Benchmarking hybrid assembly approaches for genomic analyses of bacterial pathogens using Illumina and Oxford Nanopore sequencing

Abstract Background We benchmarked the hybrid assembly approaches of MaSuRCA, SPAdes, and Unicycler for bacterial pathogens using Illumina and Oxford Nanopore sequencing by determining genome completeness and accuracy, antimicrobial resistance (AMR), virulence potential, multilocus sequence typing (...

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Autors principals:	Zhao Chen, David L. Erickson, Jianghong Meng
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2020-09-01
Col·lecció:	BMC Genomics
Matèries:	Illumina sequencing Oxford Nanopore sequencing Hybrid assembly MaSuRCA SPAdes Unicycler
Accés en línia:	http://link.springer.com/article/10.1186/s12864-020-07041-8
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