Smooth muscle cell fate decisions decipher a high-resolution heterogeneity within atherosclerosis molecular subtypes

Abstract Background Mounting evidence has revealed the dynamic variations in the cellular status and phenotype of the smooth muscle cell (SMC) are vital for shaping the atherosclerotic plaque microenvironment and ultimately mapping onto heterogeneous clinical outcomes in coronary artery disease. Cur...

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Principais autores:	Ge Zhang, Zaoqu Liu, Jinhai Deng, Long Liu, Yu Li, Siyuan Weng, Chunguang Guo, Zhaokai Zhou, Li Zhang, Xiaofang Wang, Gangqiong Liu, Jiacheng Guo, Jing Bai, Yunzhe Wang, Youyou Du, Tao-Sheng Li, Junnan Tang, Jinying Zhang
格式:	Artigo
语言:	Inglês
出版:	BMC 2022-12-01
丛编:	Journal of Translational Medicine
主题:	Atherosclerosis Smooth muscle cell-based Single-cell RNA-seq Cell fate decisions Molecular subtypes Heterogeneity
在线阅读:	https://doi.org/10.1186/s12967-022-03795-9
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