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ZNF143 inhibits hepatocyte mitophagy and promotes non-alcoholic fatty liver disease by targeting increased lncRNA NEAT1 expression to activate ROCK2 pathway

Background: Nonalcoholic fatty liver disease (NAFLD) is the most common hepatic disorders worldwide. The mitophagy is suggested to be repressed in NAFLD, but the mechanism remains to be elucidated. Methods: NAFLD cell and mouse models were established by treating with free fatty acid (FFA) and feedi...

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Hlavní autoři: Yujie Dong, Minjie Hu, Kewei Tan, Rongjuan Dai
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis Group 2023-12-01
Edice:Epigenetics
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On-line přístup:http://dx.doi.org/10.1080/15592294.2023.2239592
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