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Constitutively active 5-HT receptors: An explanation of how 5-HT antagonists inhibit gut motility in species where 5-HT is not a enteric neurotransmitter ?

Antagonists of 5-Hydroxytryptamine (5-HT) receptors are well known to inhibit gastrointestinal (GI)-motility and transit in a variety of mammals, including humans. Originally, these observations had been interpreted by many investigators (including us) as evidence that endogenous 5-HT plays a major...

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Hlavní autor: Nick eSpencer
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015-12-01
Edice:Frontiers in Cellular Neuroscience
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On-line přístup:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00487/full
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