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A role for ATF2 in regulating MITF and melanoma development.

The transcription factor ATF2 has been shown to attenuate melanoma susceptibility to apoptosis and to promote its ability to form tumors in xenograft models. To directly assess ATF2's role in melanoma development, we crossed a mouse melanoma model (Nras(Q61K)::Ink4a⁻/⁻) with mice expressing a transc...

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Ngā kaituhi matua: Meera Shah, Anindita Bhoumik, Vikas Goel, Antimone Dewing, Wolfgang Breitwieser, Harriet Kluger, Stan Krajewski, Maryla Krajewska, Jason Dehart, Eric Lau, David M Kallenberg, Hyeongnam Jeong, Alexey Eroshkin, Dorothy C Bennett, Lynda Chin, Marcus Bosenberg, Nic Jones, Ze'ev A Ronai
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2010-12-01
Rangatū:PLoS Genetics
Urunga tuihono:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1001258&type=printable
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