Increased Extrasynaptic Glutamate Escape in Stochastically Shaped Probabilistic Synaptic Environment

Excitatory synapses in the brain are often surrounded by nanoscopic astroglial processes that express high-affinity glutamate transporters at a high surface density. This ensures that the bulk of glutamate leaving the synaptic cleft is taken up for its subsequent metabolic conversion and replenishme...

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Hlavní autoři:	Leonid P. Savtchenko, Dmitri A. Rusakov
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2022-09-01
Edice:	Biomedicines
Témata:	excitatory synapse Monte Carlo model glutamate spillover glutamate uptake synaptic cross-talk
On-line přístup:	https://www.mdpi.com/2227-9059/10/10/2406
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