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Proteomic Investigation of the Sinulariolide-Treated Melanoma Cells A375: Effects on the Cell Apoptosis through Mitochondrial-Related Pathway and Activation of Caspase Cascade

Sinulariolide is an active compound isolated from the cultured soft coral Sinularia flexibilis. In this study, we investigated the effects of sinulariolide on A375 melanoma cell growth and protein expression. Sinulariolide suppressed the proliferation and migration of melanoma cells in a concentrati...

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Principais autores: Yu-Jen Wu, Yu-Hsuan Lo, Yu-Kuei Chen, Wen-Ing Hwang, Jen-Jie Lin, Zih-Yan Yang, Jui-Hsin Su, Chien-Chih Chiu, Hsing-Hui Li
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2013-07-01
coleção:Marine Drugs
Assuntos:
melanoma
sinulariolide
proteomic
mitochondria
apoptosis
caspase cascade
Acesso em linha:http://www.mdpi.com/1660-3397/11/7/2625
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