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XPO1/CRM1 is a promising prognostic indicator for neuroblastoma and represented a therapeutic target by selective inhibitor verdinexor

Abstract Background High-risk neuroblastoma patients have a 5-year survival rate of less than 50%. It’s an urgent need to identify new therapeutic targets and the appropriate drugs. Exportin-1 (XPO1), also known as chromosomal region maintenance 1, plays important roles in the progression of tumorig...

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Principais autores: Lijia Pan, Cheng Cheng, Peiwen Duan, Kai Chen, Yeming Wu, Zhixiang Wu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2021-08-01
coleção:Journal of Experimental & Clinical Cancer Research
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Acesso em linha:https://doi.org/10.1186/s13046-021-02044-z
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