Brain-Derived Neurotrophic Factor Dysregulation as an Essential Pathological Feature in Huntington’s Disease: Mechanisms and Potential Therapeutics

Brain-derived neurotrophic factor (BDNF) is a major neurotrophin whose loss or interruption is well established to have numerous intersections with the pathogenesis of progressive neurological disorders. There is perhaps no greater example of disease pathogenesis resulting from the dysregulation of...

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Principais autores:	Andrew Speidell, Noman Bin Abid, Hiroko Yano
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-08-01
coleção:	Biomedicines
Assuntos:	polyglutamine huntingtin protein axonal transport TrkB receptor neurotrophin receptors neurodegenerative diseases
Acesso em linha:	https://www.mdpi.com/2227-9059/11/8/2275
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