Breast cancer risk prediction using Tyrer-Cuzick algorithm with an 18-SNPs polygenic risk score in a European population with below-average breast cancer incidence

Goals: To determine whether an 18 single nucleotide polymorphisms (SNPs) polygenic risk score (PRS18) improves breast cancer (BC) risk prediction for women at above-average risk of BC, aged 40–49, in a Central European population with BC incidence below EU average. Methods: 502 women aged 40–49 year...

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Detalhes bibliográficos

Principais autores:	Tjaša Oblak, Petra Škerl, Benjamin J. Narang, Rok Blagus, Mateja Krajc, Srdjan Novaković, Janez Žgajnar
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-12-01
coleção:	Breast
Assuntos:	Early breast cancer Risk prediction Polygenic risk score Tyrer Cuzick algorithm
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0960977623005660
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