RhoA‐ROCK competes with YAP to regulate amoeboid breast cancer cell migration in response to lymphatic‐like flow

Abstract Lymphatic drainage generates force that induces prostate cancer cell motility via activation of Yes‐associated protein (YAP), but whether this response to fluid force is conserved across cancer types is unclear. Here, we show that shear stress corresponding to fluid flow in the initial lymp...

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Autori principali:	Amina Mohammadalipour, Miguel F. Diaz, Megan Livingston, Adesuwa Ewere, Allen Zhou, Paulina D. Horton, Loretta T. Olamigoke, John M. Lamar, John P. Hagan, Hyun J. Lee, Pamela L. Wenzel
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2022-05-01
Serie:	FASEB BioAdvances
Soggetti:	actomyosin cytoskeleton biomechanical force ECM–receptor interactions hippo mechanotransduction motility
Accesso online:	https://doi.org/10.1096/fba.2021-00055
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