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PNBACE: an ensemble algorithm to predict the effects of mutations on protein-nucleic acid binding affinity

Abstract Background Mutations occurring in nucleic acids or proteins may affect the binding affinities of protein-nucleic acid interactions. Although many efforts have been devoted to the impact of protein mutations, few computational studies have addressed the effect of nucleic acid mutations and e...

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Principais autores: Si-Rui Xiao, Yao-Kun Zhang, Kai-Yu Liu, Yu-Xiang Huang, Rong Liu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-09-01
Colecção:BMC Biology
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Acesso em linha:https://doi.org/10.1186/s12915-024-02006-9
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