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Relationship between peripheral blood miR-146b-5p levels and lymphocyte subsets in patients with sepsis and its predictive value for prognosis: a single-center study

BackgroundSepsis is a life-threatening disease with challenges in clinical management due to delayed diagnosis and immunosuppression. Lymphopenia is a key prognostic indicator in sepsis. microRNAs (miRNAs) are recognized as key immune modulators affecting all stages of inflammation. In this study, w...

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Principais autores: Sha Cheng, Jiaojiao Wang, Pengfei Wang, Xianli Long, Huiling Liu, Xueyin Li, Xiaowei Zhang, Xuemei Zhao, Hang Sun, Chuanxin Wu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-06-01
Serier:Frontiers in Immunology
Fag:
diagnosis and prognosis of sepsis
immunomodulation
lymphocyte subsets
miR-146b-5p
sepsis
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1608576/full
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