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Understanding mechanisms of colorectal cancer chemoprevention using seAFOod polyp prevention trial outcomes and its Biobank: STOP-ADENOMA synopsis

Background The 2 × 2 factorial seAFOod trial demonstrated that aspirin and omega-3 polyunsaturated fatty acid eicosapentaenoic acid reduce colorectal polyp number (a biomarker of colorectal cancer risk) during colonoscopy surveillance in the Bowel Cancer Screening Programme. The lack of a risk and/o...

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Principais autores: Ge Sun, Hayley Fenton, Harriett Fuller, Amanda Race, Tracey Mell, Lauren Burke, Amy Downing, Colin Rees, Louise Brown, Paul Loadman, Elizabeth Williams, Mark Hull
Formato: Artigo
Idioma:Inglês
Publicado em: NIHR Journals Library 2025-11-01
coleção:Efficacy and Mechanism Evaluation
Assuntos:
aspirin
biomarkers
chemoprevention
colorectal neoplasms
eicosapentaenoic acid
precision medicine
Acesso em linha:https://doi.org/10.3310/GJMH1530
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