13C-metabolic flux analysis of ethanol-assimilating Saccharomyces cerevisiae for S-adenosyl-l-methionine production

Abstract Background Saccharomyces cerevisiae is a host for the industrial production of S-adenosyl-l-methionine (SAM), which has been widely used in pharmaceutical and nutritional supplement industries. It has been reported that the intracellular SAM content in S. cerevisiae can be improved by the a...

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Hlavní autoři:	Kenshi Hayakawa, Fumio Matsuda, Hiroshi Shimizu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2018-05-01
Edice:	Microbial Cell Factories
Témata:	Saccharomyces cerevisiae 13C-based metabolic flux analysis Ethanol metabolism Central carbon metabolism Redox balance
On-line přístup:	http://link.springer.com/article/10.1186/s12934-018-0935-6
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