An adaptation of astronomical image processing enables characterization and functional 3D mapping of individual sites of excitation-contraction coupling in rat cardiac muscle

In beating cardiomyocytes, synchronized localized Ca2+ transients from thousands of active excitation-contraction coupling sites (ECC couplons) comprising plasma and sarcoplasmic reticulum membrane calcium channels are important determinants of the heart's performance. Nevertheless, our knowledge ab...

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Detalhes bibliográficos

Principais autores:	Qinghai Tian, Lars Kaestner, Laura Schröder, Jia Guo, Peter Lipp
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2017-11-01
coleção:	eLife
Assuntos:	calcium signalling cellular cardiac physiology excitation contraction coupling realtime confocal microscopy
Acesso em linha:	https://elifesciences.org/articles/30425
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