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The constitutive activation of STAT3 gene and its mutations are at the crossroad between LGL leukemia and autoimmune disorders

Abstract Type T Large Granular Lymphocyte Leukemia (T-LGLL) is a chronic disorder characterized by the abnormal proliferation of clonal cytotoxic T cells. The intriguing association of T-LGLL with autoimmune and inflammatory diseases, the most prominent example being rheumatoid arthritis, raises que...

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Hlavní autoři: Gianpietro Semenzato, Giulia Calabretto, Antonella Teramo, Vanessa Rebecca Gasparini, Elisa Rampazzo, Gregorio Barilà, Renato Zambello
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2024-01-01
Edice:Blood Cancer Journal
On-line přístup:https://doi.org/10.1038/s41408-024-00977-0
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