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Interaction of some new 2-(substituted-thio)-quinazolin-4-ones with molybdenum hydroxylases: A pharmacophore prediction

Background: Molybdenum hydroxylases have been implicated as key oxidative enzymes in some diseases. Methods: Twenty 2-(substituted-thio)-quinazolin-4-one derivatives recently synthesized in our laboratory were examined for their inhibitory activity toward molybdenum hydroxylases. Results and conclus...

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書誌詳細
主要な著者: Hussein I. El-Subbagh, Alaa A.-M. Abdel-Aziz, Mohamed A. Al-Omar, Fatmah A. Al-Omary
フォーマット: Artigo
言語:Inglês
出版事項: SpringerOpen 2015-12-01
シリーズ:Future Journal of Pharmaceutical Sciences
主題:
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2314724515300170
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