Methylene blue therapy in addition to standard treatment for acute-phase septic shock: a pilot randomized controlled trial

PurposeMethylene blue (MB) has been used to increase blood pressure in patients with septic shock by acting on guanylate cyclase and nitric oxide synthase.ObjectiveTo determine whether the administration of MB to patients in the initial phase of septic shock leads to a reduction in the use of vasopr...

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Hlavní autoři:	Fabio Luis-Silva, Mayra Gonçalves Menegueti, Leandro Moreira Peres, Corina dos Reis Sepeda, Maria Cecília Jordani, Fabiola Mestriner, Bruno Cesar Petroski-Moraes, Joaquim Pedro Brito-de-Sousa, Ismael Artur Costa-Rocha, Bruna Lemos Cruz, Mariana Dermínio Donadel, Felipe Barizza de Souza, Gustavo Henrique Martins Reis, Fernando Bellissimo-Rodrigues, Anibal Basile-Filho, Christiane Becari, Paulo Roberto Barbosa Evora, Olindo Assis Martins-Filho, Maria Auxiliadora-Martins
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-10-01
Edice:	Frontiers in Medicine
Témata:	methylene blue septic shock lactate nitric oxide cytokines vasopressors
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fmed.2024.1431321/full
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