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Blood schizontocidal activity of methylene blue in combination with antimalarials against Plasmodium falciparum

Methylene blue (MB) is the oldest synthetic antimalarial. It is not used anymore as antimalarial but should be reconsidered. For this purpose we have measured its impact on both chloroquine sensitive and resistant Plasmodium strains. We showed that around 5 nM of MB were able to inhibit 50% of the p...

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Principais autores: Garavito G., Bertani S., Rincon J., Maurel S., Monje M.C., Landau I., Valentin A., Deharo E.
Format: Artigo
Sprog:Inglês
Udgivet: EDP Sciences 2007-06-01
Serier:Parasite
Fag:
antimalarials
Plasmodium
methylene blue
drug interactions
Online adgang:http://dx.doi.org/10.1051/parasite/2007142135
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