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Hypoxia and EGF Stimulation Regulate VEGF Expression in Human Glioblastoma Multiforme (GBM) Cells by Differential Regulation of the PI3K/Rho-GTPase and MAPK Pathways

Glioblastoma multiforme (GBM) is one of the most common and deadly cancers of the central nervous system (CNS). It is characterized by the presence of hypoxic regions, especially in the core, leading to an increase in vascularity. This increased vascularization is driven by the expression of the maj...

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Principais autores: Samer Nicolas, Sandra Abdellatef, Maria Al Haddad, Isabelle Fakhoury, Mirvat El-Sibai
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2019-11-01
סדרה:Cells
נושאים:
glioblastoma
vegf
hypoxia
egf
pi3k
mapk
rho-gtpases
גישה מקוונת:https://www.mdpi.com/2073-4409/8/11/1397
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