Fitusiran treatment modulates the ratio between alpha‐ and beta‐antithrombin isoforms

Abstract Antithrombin (AT) circulates as two distinct isoforms, alpha‐ and beta‐AT, which differ in their glycosylation profiles; alpha‐AT is fully glycosylated at positions Asn128, Asn167, Asn187, and Asn224, whereas beta‐AT lacks Asn167 glycosylation. The ratio of alpha‐AT/beta‐AT is approximately...

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Bibliographic Details

Main Authors:	Geneviève McCluskey, Hortense Maynadié, Delphine Borgel, Laurent Frenzel, Annie Harroche, Elsa Bianchini, Stephanie Roullet, Olivier D. Christophe, Cecile V. Denis, Caterina Casari, Peter J. Lenting
Format:	Artigo
Language:	Inglês
Published:	Wiley 2026-05-01
Series:	HemaSphere
Online Access:	https://doi.org/10.1002/hem3.70376
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