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Human colon organoid Transwell model for investigating epithelial growth and repair

Abstract Disruption of the intestinal epithelial barrier is a hallmark of Inflammatory Bowel Disease (IBD), yet mechanisms of epithelial repair remain poorly understood. We developed a scalable human colon organoid-derived model in a 96-well Transwell system that recapitulates the cellular diversity...

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Bibliografische gegevens
Hoofdauteurs: Xinming Tong, Loryn Holokai, Mary Keir, Mercedesz Balazs, Jing Li
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2026-06-01
Reeks:npj Biomedical Innovations
Online toegang:https://doi.org/10.1038/s44385-026-00089-3
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