Protein Homeostasis in Amyotrophic Lateral Sclerosis: Therapeutic Opportunities?

Protein homeostasis (proteostasis), the correct balance between production and degradation of proteins, is essential for the health and survival of cells. Proteostasis requires an intricate network of protein quality control pathways (the proteostasis network) that work to prevent protein aggregatio...

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Váldodahkkit:	Pamela J. Shaw, Kurt J. De Vos, Christopher P. Webster, Emma F. Smith
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2017-05-01
Ráidu:	Frontiers in Molecular Neuroscience
Fáttát:	protein homeostasis protein aggregation amyotrophic lateral sclerosis (ALS) motor neuron disease autophagy chaperonins
Liŋkkat:	http://journal.frontiersin.org/article/10.3389/fnmol.2017.00123/full
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