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Arctiin-reinforced antioxidant microcarrier antagonizes osteoarthritis progression

Abstract Loss of extracellular matrix (ECM) of cartilage due to oxidative stress injury is one of the main characteristics of osteoarthritis (OA). As a bioactive molecule derived from the traditional Chinese Burdock, arctiin exerts robust antioxidant properties to modulate redox balance. However, th...

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Gardado en:
Principais autores: Yang Liu, Mingzhuang Hou, Zejun Pan, Xin Tian, Zhijian Zhao, Tao Liu, Huilin Yang, Qin Shi, Xi Chen, Yijian Zhang, Fan He, Xuesong Zhu
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2022-06-01
Series:Journal of Nanobiotechnology
Assuntos:
Arctiin
Osteoarthritis
Extracellular matrix
NRF2
Microcarrier
Acceso en liña:https://doi.org/10.1186/s12951-022-01505-7
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