3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures

Abstract Glioblastoma (GBM) is a lethal brain cancer with no effective treatment; understanding how GBM cells respond to tumor microenvironment remains challenging as conventional cell cultures lack proper cytoarchitecture while in vivo animal models present complexity all at once. Developing a cult...

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Autors principals:	Vivian K. Lee, Rut Tejero, Nathaniel Silvia, Anirudh Sattiraju, Aarthi Ramakrishnan, Li Shen, Alexandre Wojcinski, Santosh Kesari, Roland H. Friedel, Hongyan Zou, Guohao Dai
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2025-09-01
Col·lecció:	Advanced Science
Matèries:	3D vascular model brain vascular niche glia‐vascular unit glioblastoma human brain microvasculature tumor quiescence
Accés en línia:	https://doi.org/10.1002/advs.202500689
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