A comparison of foamy and lentiviral vector genotoxicity in SCID-repopulating cells shows foamy vectors are less prone to clonal dominance
Hematopoietic stem cell (HSC) gene therapy using retroviral vectors has immense potential, but vector-mediated genotoxicity limits use in the clinic. Lentiviral vectors are less genotoxic than gammaretroviral vectors and have become the vector of choice in clinical trials. Foamy retroviral vectors h...
Збережено в:
| Автори: | , , , , |
|---|---|
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Elsevier
2016-01-01
|
| Серія: | Molecular Therapy: Methods & Clinical Development |
| Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S2329050117300207 |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|