Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy
Abstract Background We have evaluated the efficacy of targeting the toxic, oligomeric form of tau protein by passive immunotherapy in a mouse model of synucleinopathy. Parkinson’s disease and Lewy body dementia are two of the most common neurodegenerative disorders and are primarily characterized by...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BMC
2018-03-01
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| Colección: | Molecular Neurodegeneration |
| Materias: | |
| Acceso en línea: | http://link.springer.com/article/10.1186/s13024-018-0245-9 |
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