Regulation of the Human Telomerase Gene TERT by Telomere Position Effect-Over Long Distances (TPE-OLD): Implications for Aging and Cancer.

Telomerase is expressed in early human development and then becomes silenced in most normal tissues. Because ~90% of primary human tumors express telomerase and generally maintain very short telomeres, telomerase is carefully regulated, particularly in large, long-lived mammals. In the current repor...

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Bibliografische gegevens

Hoofdauteurs:	Wanil Kim, Andrew T Ludlow, Jaewon Min, Jerome D Robin, Guido Stadler, Ilgen Mender, Tsung-Po Lai, Ning Zhang, Woodring E Wright, Jerry W Shay
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Public Library of Science (PLoS) 2016-12-01
Reeks:	PLoS Biology
Online toegang:	https://doi.org/10.1371/journal.pbio.2000016
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