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Genome-Wide Association Study-Guided Exome Rare Variant Burden Analysis Identifies IL1R1 and CD3E as Potential Autoimmunity Risk Genes for Celiac Disease

Celiac disease (CeD) is a multifactorial autoimmune enteropathy characterized by the overactivation of the immune system in response to dietary gluten. The molecular etiology of CeD is still not well-understood. Therefore, this study aims to identify potential candidate genes involved in CeD pathoge...

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Главные авторы: Haifa Mansour, Babajan Banaganapalli, Khalidah Khalid Nasser, Jumana Yousuf Al-Aama, Noor Ahmad Shaik, Omar Ibrahim Saadah, Ramu Elango
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2022-02-01
Серии:Frontiers in Pediatrics
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Online-ссылка:https://www.frontiersin.org/articles/10.3389/fped.2022.837957/full
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