Frequency of Werner helicase 1367 polymorphism and age-related morbidity in an elderly Brazilian population

Werner syndrome (WS) is a premature aging disease caused by a mutation in the WRN gene. The gene was identified in 1996 and its product acts as a DNA helicase and exonuclease. Some specific WRN polymorphic variants were associated with increased risk for cardiovascular diseases. The identification o...

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Bibliografische Detailangaben

Hauptverfasser:	M.A.C. Smith, M.D.A. Silva, L.Q. Araujo, L.R. Ramos, R.W. Labio, R.R. Burbano, C.A. Peres, S.B. Andreoli, S.L.M. Payão, M.S. Cendoroglo
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Associação Brasileira de Divulgação Científica 2005-07-01
Schriftenreihe:	Brazilian Journal of Medical and Biological Research
Schlagworte:	WRN: codon 1367 polymorphism Age-related morbidities Elderly cohort study
Online-Zugang:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000700008
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