Multitarget aminated fullerene hydrogels ameliorate psoriasis by scavenging ROS, inhibiting keratinocyte hyperproliferation, and reshaping the inflammatory microenvironment

Psoriasis is a chronic inflammatory skin disease driven by oxidative stress, keratinocyte hyperproliferation, and immune dysregulation. Conventional single-target therapies frequently result in incomplete remission and disease relapse. Here, we designed amino-functionalized fullerene hydrogels (TAPC...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Meihan Liu, Bowen Li, Wei Zhou, Yicheng Lu, Yating Liu, Shiliang Chen, Yiwen Pan, Zehu Wang, Anxin Chen, Yijun Wang, Jiacheng Sun, Yuan Xu, Xin Wang, Jiawei Huo, Yang Liu, Wenhui Wang, Jinmeng Jia, Jie Li, Chunru Wang, Chunli Bai
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Tsinghua University Press 2026-06-01
Schriftenreihe:	Nano Research
Schlagworte:	fullerene psoriasis reactive oxygen species (ros) inflammation keratinocyte hyperproliferation multitarget mechanism relapse
Online-Zugang:	https://www.sciopen.com/article/10.26599/NR.2026.94908575
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