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The development and characterization of a human mesothelioma in vitro 3D model to investigate immunotoxin therapy.

Tumor microenvironments present significant barriers to penetration by antibodies and immunoconjugates. Tumor microenvironments, however, are difficult to study in vitro. Cells cultured as monolayers exhibit less resistance to therapy than those grown in vivo and an alternative research model more r...

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Principais autores: Xinran Xiang, Yen Phung, Mingqian Feng, Kunio Nagashima, Jingli Zhang, V Courtney Broaddus, Raffit Hassan, David Fitzgerald, Mitchell Ho
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2011-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC3031536?pdf=render
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