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OSCA/TMEM63 are an evolutionarily conserved family of mechanically activated ion channels

Mechanically activated (MA) ion channels convert physical forces into electrical signals, and are essential for eukaryotic physiology. Despite their importance, few bona-fide MA channels have been described in plants and animals. Here, we show that various members of the OSCA and TMEM63 family of pr...

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Principais autores: Swetha E Murthy, Adrienne E Dubin, Tess Whitwam, Sebastian Jojoa-Cruz, Stuart M Cahalan, Seyed Ali Reza Mousavi, Andrew B Ward, Ardem Patapoutian
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2018-11-01
Serier:eLife
Fag:
mechanotransduction
ion channels
OSCA
mechanically activated
Online adgang:https://elifesciences.org/articles/41844
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