Efficacy and safety of early target-controlled plasma volume replacement with a balanced gelatine solution versus a balanced electrolyte solution in patients with severe sepsis/septic shock: study protocol, design, and rationale of a prospective, randomized, controlled, double-blind, multicentric, international clinical trial

Abstract Background Sepsis is associated with capillary leakage and vasodilatation and leads to hypotension and tissue hypoperfusion. Early plasma volume replacement is required to achieve haemodynamic stability (HDS) and maintain adequate tissue oxygenation. The right choice of fluids to be used fo...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Gernot Marx, Kai Zacharowski, Carole Ichai, Karim Asehnoune, Vladimír Černý, Rolf Dembinski, Ricard Ferrer Roca, Dietmar Fries, Zsolt Molnar, Peter Rosenberger, Manuel Sanchez-Sanchez, Tobias Schürholz, Tamara Dehnhardt, Sonja Schmier, Elke von Kleist, Ute Brauer, Tim-Philipp Simon
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2021-06-01
סדרה:	Trials
נושאים:	Colloids Gelatine Critically ill Sepsis Resuscitation Fluid management
גישה מקוונת:	https://doi.org/10.1186/s13063-021-05311-8
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!