Trophoblast-Targeted Nanomedicine Modulates Placental sFLT1 for Preeclampsia Treatment

The overexpressed soluble fms-like tyrosine kinase 1 (sFLT-1) in placenta is considered to be a potential therapeutic target for preeclampsia (PE). How to achieve efficient intervention of sFLT1 expression in the placenta is an urgent problem to be solved. PEG-PLA nanoparticle generated by double-em...

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Hlavní autoři:	Lei Li, Huijun Yang, Pengzheng Chen, Tao Xin, Qian Zhou, Dan Wei, Yanan Zhang, Shan Wang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2020-02-01
Edice:	Frontiers in Bioengineering and Biotechnology
Témata:	nanoparticles placental CSA binding peptide sFLT1 preeclampsia therapeutic strategy
On-line přístup:	https://www.frontiersin.org/article/10.3389/fbioe.2020.00064/full
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