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Identification of Novel Genetic Regulatory Region for Proprotein Convertase FURIN and Interferon Gamma in T Cells

The proprotein convertase enzyme FURIN promotes the proteolytic maturation of pro-proteins and thereby it serves as an important factor for maintaining cellular homeostasis. In T cells, FURIN is critical for maintaining the T regulatory cell dependent peripheral immune tolerance and intact T helper...

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Autores principales: Zsuzsanna Ortutay, Anna Grönholm, Melina Laitinen, Melinda Keresztes-Andrei, Ismail Hermelo, Marko Pesu
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021-02-01
Colección:Frontiers in Immunology
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Acceso en línea:https://www.frontiersin.org/articles/10.3389/fimmu.2021.630389/full
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