Transforming growth factor-β1/Smad/connective tissue growth factor axis: The main pathway in radiation-induced fibrosis of osteoradionecrosis?

Introduction: Osteoradionecrosis (ORN) of the mandible is a serious complication following radiation therapy for malignancies of the head and neck. Radiation-induced fibrosis (RIF) is a new theory that accounts for the damage to normal tissues after radiotherapy, and the radiation-induced fibroatrop...

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Principais autores:	Qian Wei Zhuang, Zhi Yuan Zhang, Guang Long Liu, Shui Ting Fu, Yue He
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wolters Kluwer Medknow Publications 2013-01-01
coleção:	Dental Hypotheses
Assuntos:	Connective tissue growth factor osteoradionecrosis radiation-induced fibrosis transforming growth factor-β1/Smad/connective tissue growth factor axis transforming growth factor-β1
Acesso em linha:	http://www.dentalhypotheses.com/article.asp?issn=2155-8213;year=2013;volume=4;issue=4;spage=122;epage=126;aulast=Zhuang
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