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Virus-Like Particle Mediated CRISPR/Cas9 Delivery for Efficient and Safe Genome Editing

The discovery of designer nucleases has made genome editing much more efficient than before. The designer nucleases have been widely used for mechanistic studies, animal model generation and gene therapy development. However, potential off-targets and host immune responses are issues still need to b...

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Hlavní autoři: Pin Lyu, Luxi Wang, Baisong Lu
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2020-12-01
Edice:Life
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On-line přístup:https://www.mdpi.com/2075-1729/10/12/366
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