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Rho GDP-Dissociation Inhibitor 2 Inhibits C-X-C Chemokine Receptor Type 4-Mediated Acute Lymphoblastic Leukemia Cell Migration

Although we currently have a good understanding of the role C-X-C chemokine receptor type 4 (CXCR4) plays in T cell acute lymphoblastic leukemia (T-ALL), the mechanism of CXCR4-mediated T-ALL migration remains elusive. Therefore, we focus on the downstream signals of CXCR4 that contribute to T-ALL c...

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Autores principales: Jixian Luo, Junting Wang, Huiguang Zheng, Lan Wang
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020-08-01
Colección:Frontiers in Oncology
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Acceso en línea:https://www.frontiersin.org/article/10.3389/fonc.2020.01512/full
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