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Systematic evaluation of intratumoral and peripheral BCR repertoires in three cancers

The current understanding of humoral immune response in cancer patients suggests that tumors may be infiltrated with diffuse B cells of extra-tumoral origin or may develop organized lymphoid structures, where somatic hypermutation and antigen-driven selection occur locally. These processes are belie...

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Hauptverfasser: Sofia V Krasik, Ekaterina A Bryushkova, George V Sharonov, Daria S Myalik, Elizaveta V Shurganova, Dmitry V Komarov, Irina A Shagina, Polina S Shpudeiko, Maria A Turchaninova, Maria T Vakhitova, Igor V Samoylenko, Dimitr T Marinov, Lev V Demidov, Vladimir E Zagaynov, Dmitriy M Chudakov, Ekaterina O Serebrovskaya
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications Ltd 2025-01-01
Schriftenreihe:eLife
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Online-Zugang:https://elifesciences.org/articles/89506
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