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AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles

Summary: The autophagy pathway is an essential facet of the innate immune response, capable of rapidly targeting intracellular bacteria. However, the initial signaling regulating autophagy induction in response to pathogens remains largely unclear. Here, we report that AMPK, an upstream activator of...

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Bibliografski detalji
Glavni autori: Truc T. Losier, Mercy Akuma, Olivia C. McKee-Muir, Nicholas D. LeBlond, Yujin Suk, Reham M. Alsaadi, Zhihao Guo, Ryan Reshke, Subash Sad, François-Xavier Campbell-Valois, Derrick J. Gibbings, Morgan D. Fullerton, Ryan C. Russell
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019-02-01
Serija:Cell Reports
Online pristup:http://www.sciencedirect.com/science/article/pii/S2211124719300919
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