RETRACTED: A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice

Metabolic endotoxemia has been suggested to play a role in the pathophysiology of metaflammation, insulin-resistance and ultimately type-2 diabetes mellitus (T2DM). The role of endogenous antimicrobial peptides (AMPs), such as the cathelicidin LL-37, in T2DM is unknown. We report here for the first...

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Principais autores:	Shireen Mohammad, Sura Al Zoubi, Debora Collotta, Nadine Krieg, Bianka Wissuwa, Gustavo Ferreira Alves, Gareth S. D. Purvis, Giuseppe Danilo Norata, Andrea Baragetti, Alberico Luigi Catapano, Egle Solito, Elisabeth Zechendorf, Tobias Schürholz, Wilmar Correa-Vargas, Klaus Brandenburg, Sina M. Coldewey, Massimo Collino, Muhammad M. Yaqoob, Lukas Martin, Christoph Thiemermann
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-07-01
coleção:	Frontiers in Immunology
Assuntos:	peptide 19-2.5 high-fat diet type-2 diabetes antimicrobial peptide insulin resistance steatohepatitis
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.701275/full
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