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Smoking cessation reverses DNA double-strand breaks in human mononuclear cells.

OBJECTIVE:Cigarette smoking is a major risk factor for atherosclerotic cardiovascular disease, which is responsible for a significant proportion of smoking-related deaths. However, the precise mechanism whereby smoking induces this pathology has not been fully delineated. Based on observation of DNA...

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Principais autores: Mari Ishida, Takafumi Ishida, Satoshi Tashiro, Hitomi Uchida, Chiemi Sakai, Naoya Hironobe, Katsuya Miura, Yu Hashimoto, Koji Arihiro, Kazuaki Chayama, Yasuki Kihara, Masao Yoshizumi
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2014-01-01
叢編:PLoS ONE
在線閱讀:http://europepmc.org/articles/PMC4122368?pdf=render
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