Dysregulation of tRNA methylation in cancer: Mechanisms and targeting therapeutic strategies

Abstract tRNA is the RNA type that undergoes the most modifications among known RNA, and in recent years, tRNA methylation has emerged as a crucial process in regulating gene translation. Dysregulation of tRNA abundance occurs in cancer cells, along with increased expression and activity of tRNA met...

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Detalhes bibliográficos

Principais autores:	Wenbin Yuan, Rui Zhang, Hao Lyu, Shuai Xiao, Dong Guo, Qi Zhang, Declan William Ali, Marek Michalak, Xing-Zhen Chen, Cefan Zhou, Jingfeng Tang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2024-07-01
coleção:	Cell Death Discovery
Acesso em linha:	https://doi.org/10.1038/s41420-024-02097-x
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