Dietary arachidonate in milk replacer triggers dual benefits of PGE2 signaling in LPS-challenged piglet alveolar macrophages

Abstract Background Respiratory infections challenge the swine industry, despite common medicinal practices. The dual signaling nature of PGE2 (supporting both inflammation and resolution) makes it a potent regulator of immune cell function. Therefore, the use of dietary long chain n-6 PUFA to enhan...

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Bibliografische Detailangaben

Hauptverfasser:	Kathleen R. Walter, Xi Lin, Sheila K. Jacobi, Tobias Käser, Debora Esposito, Jack Odle
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2019-02-01
Schriftenreihe:	Journal of Animal Science and Biotechnology
Schlagworte:	Arachidonic acid Cyclooxygenase Eicosanoid Eicosapentaenoic acid Inflammation Lipid mediator class switch
Online-Zugang:	http://link.springer.com/article/10.1186/s40104-019-0321-1
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