Etomoxir mediates differential metabolic channeling of fatty acid and glycerol precursors into cardiolipin in H9c2 cells

We examined the effect of etomoxir treatment on de novo cardiolipin (CL) biosynthesis in H9c2 cardiac myoblast cells. Etomoxir treatment did not affect the activities of the CL biosynthetic and remodeling enzymes but caused a reduction in [1-14C]palmitic acid or [1-14C]oleic acid incorporation into...

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Detalhes bibliográficos

Principais autores:	Fred Y. Xu, William A. Taylor, Jeffrey A. Hurd, Grant M. Hatch
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2003-02-01
coleção:	Journal of Lipid Research
Assuntos:	heart cells mitochondria phospholipids glycerol kinase 1,2-diacyl-sn-glycerol acyltransferase phosphatidate phosphohydrolase
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0022227520312293
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